Straggling to weakly erect perennial herb 0.6-2.5 m tall. Stems 4-angled , hairy.  Leaves ovate to ovate lanceolate, 3-8 cm long, pubescent above, densely white hairy beneath; margin serrate -crenate; petiole 2-20 mm long. Inflorescence a very lax terminal panicle, composed of many10-24-flowered branched heads. Flowers small, white with purple  spots at the base of the lobes.

Isodon ramosissimus is used to treat cough and colds. In the Western Province, Isodom ramisissimus leaves are used to treat bone diseases, said Mitari Emmanuel.